lipodrene vs hydroxyelite

Lipodrene VS HydroxyElite – Hi Tech Fat Burners Review

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Hi Tech Pharmaceuticals is known for pushing the envelope on many things when it comes to creating hardcore supplements. Leaving no doubt that a product will pack a punch and leave the user feeling the effects of their stimulant driven products, they have rolled out numerous pre-workouts and thermogenics that are known for being some of the hardest hitting on the market.

With this in mind, High Tech Pharmaceuticals Lipodrene and Hydroxyelite are no exception. Both are hard hitting, stimulant based thermogenic products that have somewhat ‘edgy’ ingredients at their core for amping up the intensity and powering the product. Thought similar, they do have some key differences, so the purpose of this article is to dive into some compare and contrast and take a look at what makes them special.

lipodrene fat burnerLipodrene

Starting out with Lipodrene, the product highlights are as such:

  • 35mg focus-enhancing DMAA
  • 25mg Thermo-RX Ephedra Extract (with the ephedrine alkaloids removed)
  • 100mg caffeine
  • Acacia rigidula extract for its mood-enhancing and fat-attacking PEA alkaloids
  • Other appetite suppressing ingredients

Right off of the bat, you see that there is no joke when it comes to the ingredients that drive Lipodrene, fueled by DMAA and ephedra extract at the heart of the stimulant base. There are a lot of other ingredients that go into Lipodrene as well, so let’s next take a peek at what it all includes and a few brief notes of what they do.

Caffeine Anhydrous – 100mg

  • Potent CNS stimulant that antagonizes adenosine receptors
  • Enhances mental focus and energy
  • Increase cognition and reaction time
  • Contributes to fat loss by helping release more fat cells and reduces fat storage

Ephedra Extract – 25mg

  • Ephedra free extract (not the banned alkaloids)
  • Derivative of the plant Ephedraceae
  • Concentrated active material that has been drawn out by chemical means from the raw herb; extracts, or removes, the active alkaloid content
  • Shown to be effective in the weight loss field as appetite suppressant; Promotes weight loss and energy
  • Extract contains alkaloids pseudoephedrine, norpseudoephedrine and methylpseudoephedrine but does NOT contain ephedrine itself or methylephedrine

Senegalia Berlandieri Extract – 125mg (Formerly Acacia rigidula)

  • Southern Texan plant
  • Shown to have fat burning and mood enhancing compounds
  • Supplies PEA (phenylethylamine) alkaloids including methylsynephrine, B-Phenylethylamine, and N-Methyl-B-Phenylethylamine
  • Has a mild stimulatory effect and great boost in mood

Synephrine HCl – 25mg

  • Also known as bitter orange extract
  • Known as a safe alternative to ephedra
  • Helps facilitate utilization of energy substrates
  • Helps stimulate metabolic processes and favors uptake of amino acids into muscle
  • May help suppress appetite
  • Stimulates fat loss and energy expenditure
  • Doesn’t increase heart rate or blood pressure

DMAA – 35mg

  • Powerful neural stimulant with structure similar to ephedrine and adrenaline
  • Classified as sympathomimetic amine extracted from Geranium
  • Triggers the release of norepinephrine – Creates ‘euphoric’ sensation
  • May also provide appetite suppression effects


  • Derived from cacao seeds; structurally similar to caffeine
  • Exerts effects similar to caffeine; Known to have smoother, less intense effects
  • Helps to offset potential crash that may happen when taking stimulants

Green Tea Extract – 45mg EGCG

  • Shown to aid in inducing lipolysis (fat breakdown)
  • High polyphenol and catechin content offer numerous health benefits
  • Effects further amplified when combined with caffeine

Hoodia Extract

  • Short, desert shrub; derived from Hoodia gordonii
  • Known for appetite suppression effects

Cassia Nomame Extract

  • Medicinal plant native to China that currently grows wildly in many regions and areas all over the world
  • Interacts with lipase enzyme; shown to inhibit lipase potentially preventing fat storage


  • Compound found in grapefruits
  • May have mild weight loss effects
  • Known as a potent energy booster
  • Inhibits PDE enzymes

6,7 Dihydroxybergamottin (Fruit)

  • Compound found in grapefruits
  • Inhibits enzymes (CYP3A4); Prevents breakdown of active ingredients
  • Prolongs half-life of other ingredients for longer effects

5-Methoxytryptamine HCl and 5-HTP

  • 5-HTP is synthesized from tryptophan; later converted to serotonin
  • Used to help with sleep or combat stress and anxiety
  • Also shown to combat obesity and suppress appetite
  • 5-MOT is naturally occurring in the body and is the same molecularly as serotonin
  • Prevents serotonin from being broken down in the body
  • Increases circulating levels of serotonin

Yohimbine HCl

  • Increases adrenaline levels in the body
  • Stimulates Alpha receptors to help trigger fat loss
  • May help reduce body fat in ‘trouble areas’
  • Reduces hunger sensation



Now, let’s take a look at Hydroxyelite. Known as one of the greatest thermogenics of all time, USPLabs OxyElite Pro was a hard hitting, energy packed powerhouse that quickly became a favorite. However, due to the nature of the supplement industry and an ever changing landscape, the once popular OxyElite Pro no longer is available and has left many searching for a suitable replacement. That’s where Hi Tech Pharmaceuticals steps in with their recreated and what most would consider improved HydroxyElite.

Hydroxyelite highlights according to Hi Tech Pharmaceutials include:

  • Extreme Thermogenic
  • Intense Stimulant
  • Increase Energy
  • Suppress Appetite
  • Boost Metabolism
  • Featuring DMAA

As you can see, just like Lipodrene, Hi Tech Pharmaceuticals wasn’t messing around when it came to creating HydroxyElite Pro. Based very closely on the original USPLabs OxyElite Pro, it takes it as step further. Let’s take a look at the ingredient profile:

Bauhinia Purpurea L. (Leaf And Pod) Extract

  • Shown to possibly have thyroid boosting effects
  • Converts thyroid hormones into fat burning beneficial ratios; acts to convert T4 to T3
  • Possibly increases T4 by 37%; Boost T3 by 83%
  • Shown to counteract declining T3/T4 levels

Bacopa Monnieri

  • Nootropic herb used in traditional medicine for longetivity and cognitive enhancement
  • Supplementation can reduce anxiety and improve memory formation
  • Has secondary effects as thyroid booster; works synergistically with Bauhinia Purpurea

DMAA (1,3 Dimethylamylamine)

  • Powerful neural stimulant with structure similar to ephedrine and adrenaline
  • Classified as sympathomimetic amine extracted from Geranium
  • Triggers the release of norepinephrine – Creates ‘euphoric’ sensation
  • May also provide appetite suppression effects

Cirsium Oligophyllum (Whole Plant) Extract

  • Helps the body burn fat by exciting beta-adrenergic receptors
  • Boosts energy expenditure by increasing action of uncoupling proteins (UCP1)
  • Stimulates release epinephrine; increases lipolysis
  • Helps mobilization of brown fat tissue

Rauwolscine – 5mg

  • More commonly known as alpha-yohimbine
  • Powerful Alpha-2 agonist; prevents fat storage and encourages fat mobilization
  • Potent stimulatory effects

Garcinia Cambogia Extract (fruit rind)

  • Fruit known to enhance culinary experience of foods
  • Enhances satiety from meals
  • Believe mechanism for lipolysis is the Hydroxycitric acid works by inhibiting citric acid lipase


Lipodrene vs HydroxyElite – The Differences & Verdict

Comparing Lipodrene and HydroxyElite, they do indeed have some major differences in ingredient profile. Most notably, both feature the often controversial DMAA as the main stimulant driven component. After that, Lipodrene’s main difference is the inclusion of ephedra extract, another controversial ingredient to some.

Overall, the Lipodrene has what most would regard as a harder hitting simulant profile including both the DMAA and ephedra extract. It does have a lot of other ingredients for helping the user with fat loss and the main emphasis is the appetite suppression effects with some extra targeting of fat loss from the inclusion of the Yohimbe which is an alpha-receptor agonist.

On the other hand, HydroxyElite has a strong stimulant base as well, but it does seem a bit toned down compared to the Lipodrene to some degree. It will still hit hard, but the emphasis is more so on the appetite suppression component and what many would consider more ‘modern’ modifications for the fat loss area. Another main difference in that regard is utilizing Rauwolscine in place of traditional Yohimbe, which is known for having less side effects associated with Yohimbe and providing an overall ‘cleaner’ feel.

Between the two, you really can’t go wrong. Personally, we like the HydroxyElite a bit better than the Lipodrene due to the cleaner feel, without so many stimulants and the true ‘fat burning’ ingredients aspect is better. However, if you’re a stim junkie and want extreme energy or just are looking for a more familiar feeling that you would get from old school ephedra products, they you won’t go wrong picking up Lipodrene instead.